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Related Experiment Videos

Total and split renal function assessed by ultrasound Doppler techniques.

T Yura1, Y Takamitsu, S Yuasa

  • 1Second Department of Internal Medicine, Kagawa Medical School, Japan.

Nephron
|January 1, 1991
PubMed
Summary

Ultrasound Doppler

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Area of Science:

  • Nephrology
  • Medical Imaging
  • Cardiovascular Physiology

Background:

  • Assessing total and split renal function is crucial for diagnosing and managing kidney diseases.
  • Traditional methods for evaluating renal function can be invasive or time-consuming.
  • Non-invasive techniques for renal function assessment are highly desirable in clinical practice.

Purpose of the Study:

  • To evaluate the utility of ultrasound Doppler in assessing total and split renal functions.
  • To determine the correlation between renal arterial blood flow patterns and established measures of renal function.
  • To explore the clinical applicability of Doppler ultrasound for individual renal function assessment.

Main Methods:

  • Utilized a renal-time pulsed ultrasonic echo-Doppler device (2.5 MHz) via a translumbar approach.

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  • Measured renal arterial blood flow parameters, including peak diastolic (D) to systolic (S) velocity ratio and acceleration time.
  • Compared Doppler-derived parameters with p-aminohippurate clearance, creatinine clearance, and radionuclide-based split renal glomerular filtration rate (GFR).

    • Main Results:

    • The D/S velocity ratio showed a strong correlation with both p-aminohippurate and creatinine clearance.
    • Acceleration time did not correlate significantly with either clearance measure.
    • The D/S ratio demonstrated good correlation with split renal GFR determined by radionuclide methods.

    Conclusions:

    • Pulsed Doppler ultrasound measurement of renal arterial blood flow is a valuable tool for assessing total renal function.
    • The D/S velocity ratio derived from Doppler ultrasound effectively estimates split renal function.
    • Ultrasound Doppler offers a promising non-invasive method for evaluating renal function in clinical settings.