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Experimental Infection with Listeria monocytogenes as a Model for Studying Host Interferon-γ Responses
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Secretion of human interferon-beta 1b by recombinant Lactococcus lactis

Zhong Zhuang1, Zhi-Gang Wu, Min Chen

  • 1State Key Laboratory of Microbial Technology, Shandong University, Jinan, Shandong 250100, People's Republic of China.

Biotechnology Letters
|June 26, 2008
PubMed
Summary

Recombinant human interferon-beta (huIFN-beta) was successfully produced in Lactococcus lactis. This food-grade bacterium can deliver bioactive huIFN-beta for potential therapeutic applications in inflammatory disorders.

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