Infected thoracoabdominal aortic aneurysms including the major abdominal branches in 4 cases

Hitoshi Inafuku1, Shigenobu Senaha, Yuji Morishima

  • 1Thoracic and Cardiovascular Surgery, Division Department of Bioregulatory Medicine, Faculty of Medicine, University of the Ryukyus, Nishihara, Japan.

Insights

This study reports on surgical repair for four infected thoracoabdominal aortic aneurysms (TAAA). The described technique, including graft replacement and artery reimplantation, showed promise in preventing graft infection post-surgery.

Area of Science:

  • Vascular Surgery
  • Aortic Aneurysm Research
  • Infectious Disease Management in Surgery

Background:

  • Infected thoracoabdominal aortic aneurysms (TAAA) pose significant surgical challenges.
  • Repair often involves complex reconstruction, especially when abdominal branches are involved.
  • High rates of morbidity and mortality are associated with TAAA infections.

Observation:

  • Four cases of infected TAAA with involvement of abdominal branches were surgically repaired.
  • The procedure included debridement, in situ four-branched Dacron graft replacement, and omental wrapping.
  • Reimplantation of intercostal and lumbar arteries was performed to prevent spinal ischemia.

Findings:

  • One hospital death (25%) occurred, and one patient (25%) experienced postoperative paraplegia.
  • No instances of postoperative graft infection were observed during a mean follow-up of 15 months.
  • Intravenous and lifelong oral antibiotic administration was part of the postoperative management.

Implications:

  • The presented surgical strategy may effectively prevent postoperative graft infection in complex TAAA cases.
  • Careful management of visceral and spinal artery perfusion is crucial for successful TAAA repair.
  • Further research is warranted to validate this approach in a larger patient cohort.

Related Concept Videos

Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...
Aneurysm I: Introduction01:30

Aneurysm I: Introduction

An aortic aneurysm is a localized outpouching or dilation at a weak point in the artery wall. It may involve different parts of the aorta, such as the abdominal aorta, aortic arch, or thoracic aorta.Etiological factorsSeveral disorders are associated with aortic aneurysms.Congenital causes, such as primary connective tissue disorders like Marfan syndrome, impact the integrity and strength of connective tissues, notably affecting the aorta. Marfan syndrome is a genetic disorder that specifically...
Aneurysm III: Interprofessional Care01:26

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...
Abdominal Aorta01:25

Abdominal Aorta

Once the aorta traverses the diaphragmatic plane at the aortic hiatus, it is known as the abdominal aorta. This anatomical structure is positioned leftward of the spinal column, encased within a cocoon of adipose tissue behind the peritoneal cavity. It terminates at the L4 vertebra, where it splits into the common iliac arteries. Prior to this bifurcation, the abdominal aorta gives rise to several vital branches.
The celiac trunk, a singular artery, divides into the left gastric artery, which...
Thoracic Aorta01:15

Thoracic Aorta

The thoracic section of the aorta begins at the T5 vertebra and extends to the T12 level at the diaphragm, initially progressing through the mediastinum to the left of the spinal column. Throughout its course in the thoracic segment, the thoracic aorta emits various offshoots known collectively as visceral and parietal branches. The branches that predominantly supply blood to visceral organs are termed visceral branches and include bronchial, pericardial, esophageal, and mediastinal arteries,...
The Aorta01:14

The Aorta

The aorta is the largest artery in the human body. It originates from the left ventricle of the heart and extends down to the abdomen, where it splits into two smaller arteries. Structurally, it can be divided into four main parts: the ascending aorta, the aortic arch, the thoracic aorta, and the abdominal aorta.
The average diameter of the aorta is approximately 2-3 cm, but the size can vary depending on the section of the aorta and the individual's age, sex, and body size. The aorta is...