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[Mammographic control after quadrantectomy and radiation therapy].
V Pignatelli1, C Campassi, A Calderazzi
1U.O. Radiodiagnostica II, USL 12, Pisa.
La Radiologia Medica
|June 1, 1991
Summary
Mammography effectively detects breast cancer recurrence after surgery and radiation, but interpreting post-treatment changes remains challenging. Careful follow-up is crucial for accurate diagnosis.
Area of Science:
- Oncology
- Radiology
- Medical Imaging
Background:
- Combined surgery and radiation therapy are standard breast cancer treatments.
- Mammography is vital for post-treatment surveillance to detect early recurrences.
- Evaluating changes in treated breasts requires understanding post-irradiation effects.
Purpose of the Study:
- To assess the efficacy of mammography in detecting breast cancer recurrence after combined treatment.
- To analyze mammographic findings in patients treated with local excision, axillary dissection, and irradiation.
- To correlate mammographic findings with histological changes and identify diagnostic challenges.
Main Methods:
- Follow-up of 43 breast cancer patients treated with local excision, axillary dissection, and irradiation.
- Serial mammography performed at 6, 12, and 24 months post-treatment.
- Correlation of radiological findings with histopathological results from excisional biopsies.
Main Results:
- 88.3% of patients showed abnormal mammographic patterns post-treatment.
- Common findings included skin thickening (83.7%), increased parenchymal density (76.7%), and architectural distortion (39.5%).
- Mammography identified suspicious findings in 7 patients, with recurrence confirmed in 4 (57.1%) via biopsy; however, 3 cases showed benign changes mimicking malignancy.
Conclusions:
- Mammography is a valuable tool for breast cancer recurrence detection post-treatment.
- Interpreting post-irradiation changes on mammograms can be difficult, leading to potential misdiagnosis.
- A structured clinical and mammographic follow-up schedule is recommended, aligning with existing literature.