Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Topical intranasal cortisone therapy].

P Bellioni1, R W Pezzuto, A Artuso

  • 1Istituto di Clinica otorinolaringoiatrica, Università cattolica del Sacro Cuore, Roma.

Recenti Progressi in Medicina
|April 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Longitudinal Evaluation of Bone Mineral Density and Bone Metabolism Markers in Patients with Indolent Systemic Mastocytosis Without Osteoporosis.

Calcified tissue international·2016
Same author

The role of septal surgery in cosmetic rhinoplasty.

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·2013
Same author

Arcanobacterium haemolyticum: two case reports.

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·2008
Same author

[Rehabilitation in Parkinson disease].

Giornale italiano di medicina del lavoro ed ergonomia·2007
Same author

Pauci-symptomatic large epidermoid cyst of cerebellopontine angle: case report.

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·2004
Same author

Canal wall down tympanoplasty surgery with or without ossiculoplasty in cholesteatoma: hearing results.

Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale·2004

New topical intranasal corticosteroids offer effective, safe long-term treatment for allergic rhinitis and other respiratory conditions. Research highlights their high efficacy and minimal side effects for improved patient outcomes.

Area of Science:

  • Pharmacology
  • Allergology
  • Pulmonology

Background:

  • Recent advancements in corticosteroid research have yielded new topical intranasal formulations.
  • These corticosteroids exhibit high target organ activity with minimal systemic or local side effects.
  • Topical intranasal corticosteroid therapy is now a cornerstone for allergic rhinitis and beneficial for various nasal and bronchopulmonary diseases.

Purpose of the Study:

  • To review the general aspects of topical intranasal corticosteroids, including pharmacology, pharmacokinetics, toxicology, side effects, and contraindications.
  • To analyze currently available topical intranasal corticosteroid drugs used internationally and in Italy.
  • To compare the efficacy of different topical intranasal glucocorticoids and other therapeutic options.

Main Methods:

Related Experiment Videos

  • Literature review and analysis of personal clinical experience.
  • Pharmacological and pharmacokinetic profiling of intranasal corticosteroids.
  • Comparative efficacy analysis of various topical intranasal glucocorticoids.

Main Results:

  • Newer corticosteroids demonstrate significant efficacy with an improved safety profile for long-term use.
  • Topical intranasal corticosteroids are indispensable for allergic rhinitis and useful in chronic rhinitis, nasal polyposis, asthma, and COPD.
  • Comparative analysis provides insights into the relative effectiveness of different agents.

Conclusions:

  • Topical intranasal corticosteroids represent a safe and effective therapeutic option for a range of respiratory conditions.
  • The development of these agents has significantly improved management strategies for allergic rhinitis and related diseases.
  • Further comparative studies reinforce their role as a primary treatment modality.