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Updated: Jul 4, 2026

Fertility Preservation Through Oocyte Vitrification: Clinical and Laboratory Perspectives
Published on: September 16, 2021
A case of oocyte and embryo vitrification resulting in clinical pregnancy
Meghan B Oakes1, Claudia Messias Gomes, Joyce Fioravanti
1Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, Michigan 48109-0617, USA.
Objective:
To examine a case of clinical pregnancy following oocyte and day 3 embryo vitrification.
Design:
Case report.
Setting:
Huntington Centro de Medicina Reprodutiva, a private infertility clinic, in São Paolo, Brazil.
Patient(S):
A 31-year-old woman, gravida 1, para 1, with polycystic ovary syndrome.
Intervention(S):
In vitro fertilization with oocyte and embryo vitrification.
Main Outcome Measure(S):
Clinical pregnancy defined as fetal cardiac activity on ultrasound examination.
Result(S):
Transvaginal ultrasound examination, at 7 6/7 weeks, revealed a single live intrauterine pregnancy with positive cardiac activity.
Conclusion(S):
Although further research is needed, this case suggests that repeat vitrification and warming of oocytes and embryos not only are possible but can result in pregnancy.
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