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Effect of progressive addition lenses on myopia progression in Japanese children: a prospective, randomized,
Satoshi Hasebe1, Hiroshi Ohtsuki, Takafumi Nonaka
1Department of Ophthalmology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan. shasebe@md.okayama-u.ac.jp
Insights
Progressive addition lenses (PALs) slowed myopia progression in Japanese children compared to single-vision lenses (SVLs). Early use of PALs demonstrated a greater benefit in slowing myopia progression.
Area of Science:
- Ophthalmology
- Pediatric Optometry
Background:
- Myopia progression is a significant concern in childhood.
- Understanding effective interventions is crucial for managing pediatric refractive errors.
Purpose of the Study:
- To evaluate the clinical effectiveness of progressive addition lenses (PALs) versus single-vision lenses (SVLs) in slowing myopia progression in Japanese children.
- To compare the impact of early versus later use of PALs.
Main Methods:
- A prospective, randomized, double-masked, crossover trial involving 92 children aged 6-12 years with myopia.
- Participants wore either PALs (+1.50 D near addition) or SVLs for 18 months, followed by the alternative for another 18 months (3-year follow-up).
- Myopia progression was measured using cycloplegic autorefraction.
Main Results:
- Progressive addition lenses (PALs) showed a statistically significant effect in slowing myopia progression compared to single-vision lenses (SVLs) (P = 0.0007).
- A mean difference of 0.17 D in myopia progression was observed over 18 months.
- A significant treatment-by-period interaction indicated that earlier use of PALs resulted in slower myopia progression.
Conclusions:
- Progressive addition lenses (PALs) can slow myopia progression in Japanese children, though the effect size is modest.
- The findings suggest that initiating PAL wear earlier in childhood may yield greater benefits for myopia control.
- Early application of PALs is likely more beneficial for the studied age and refractive error ranges.
Purpose:
This prospective, randomized, double-masked, crossover trial was conducted to evaluate the clinical effectiveness of progressive addition lenses (PALs) compared with single-vision lenses (SVLs) on myopia progression in Japanese children.
Methods:
Ninety-two children fulfilling the inclusion criteria (age: 6-12 years, spherical equivalent refractive errors: -1.25 to -6.00 D) were randomly allocated to either 18 months of wearing PALs (near addition: +1.50 D) followed by 18 months of SVLs (group 1), or 18 months of wearing SVLs followed by 18 months of wearing PALs (group 2), and were followed up for 3 years (two-stage crossover design). The primary outcome measure was myopia progression, as determined by cycloplegic autorefraction.
Results:
Eighty-six (93%) children completed both treatment periods. A mixed-model, two-way analysis of variance (ANOVA) performed using 3-year data identified a significant treatment effect of PALs compared with SVLs (P = 0.0007), with a mean 18-month difference of 0.17 D (95% CI: 0.07-0.26 D). This analysis also indicated a significant period effect (P = 0.0040) and a significant treatment-by-period interaction (P = 0.0223): Group 1 showed a slower myopia progression than did group 2.
Conclusions:
The use of PALs slowed myopia progression, although the treatment effect was small, as previously reported in ethnically diverse children in the United States. The significant treatment-by-period interaction suggests that early application of PALs would probably be more beneficial for these age and refraction ranges (isrctn.org number, 28611140).
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