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Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

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Related Experiment Video

Updated: Jul 4, 2026

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Post-penetrating keratoplasty glaucoma.

Tanuj Dada¹, Anand Aggarwal, K B Minudath

¹Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, New Delhi, India. tanujdada@hotmail.com

Indian Journal of Ophthalmology

|June 27, 2008

Summary

This summary is machine-generated.

Post-penetrating keratoplasty (PK) glaucoma can cause vision loss and graft failure. Understanding its causes and management is key to preserving sight and graft survival after PK.

Related Experiment Videos

Last Updated: Jul 4, 2026

Iris Fixation via External Pentagram Suturing

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Area of Science:

Ophthalmology
Glaucoma Research
Corneal Surgery

Background:

Post-penetrating keratoplasty (PK) glaucoma is a significant cause of irreversible vision loss and corneal graft failure.
The multifactorial etiology of post-PK glaucoma necessitates a thorough understanding of its pathophysiology for effective management.

Purpose of the Study:

To elucidate the pathophysiology of post-PK glaucoma using advanced diagnostic tools.
To outline appropriate management algorithms based on a clear understanding of post-PK glaucoma mechanisms.
To discuss risk factors, intraocular pressure (IOP) assessment, and monitoring challenges in post-PK glaucoma.

Main Methods:

Review of current literature on post-PK glaucoma etiology and pathophysiology.
Discussion of diagnostic challenges including visual field and optic nerve evaluation.
Presentation of a step-wise management approach from medical therapy to surgical interventions.

Main Results:

Identified multifactorial causes and time-dependent mechanisms of post-PK glaucoma.
Detailed a management strategy encompassing medical, surgical (with/without antimetabolites), and cycloablative procedures.
Highlighted the risk of graft rejection with IOP-lowering surgeries and graft failure with cyclodestructive procedures.

Conclusions:

A comprehensive understanding of post-PK glaucoma mechanisms is crucial for optimal patient outcomes.
Careful consideration of risk-benefit ratios is essential when selecting treatment modalities.
Preventive strategies, such as using oversized grafts and iridoplasty, may minimize glaucoma incidence post-PK.