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COMT Val108/158Met polymorphism and the modulation of task-oriented behavior in children with ADHD

Sarojini Sengupta1, Natalie Grizenko, Norbert Schmitz

  • 1Department of Human Genetics, McGill University, Montreal, QC, Canada.

Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology
|June 27, 2008
PubMed
Summary

The COMT Val(108/158)Met gene variant influences task-oriented behavior in children with attention-deficit/hyperactivity disorder (ADHD). However, this genetic polymorphism does not affect how children with ADHD respond to methylphenidate (MPH) treatment.

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