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Updated: Jul 4, 2026

Detecting the Lyme Disease Spirochete, Borrelia Burgdorferi, in Ticks Using Nested PCR
Published on: February 4, 2018
An eight-year-old girl with probable Lyme disease in Hong Kong
1Department of Paediatrics, Kwong Wah Hospital, Waterloo Road, Hong Kong.
Abstract:
An eight-year-old girl presented with acute cerebellar syndrome and meningitis. Lumbar puncture showed elevated pressure. Examination of the cerebrospinal fluid showed lymphocytosis, raised protein and decreased glucose. She was initially treated with acyclovir and antituberculosis drugs with partial response. Subsequently, the antibody assay for Borrelia burgdorferi was positive and the antimicrobial regime was changed to ceftriaxone. She made a full recovery with no neurological deficit. A probable diagnosis of Lyme disease was made and the diagnostic approach to Lyme disease is discussed.
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