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The Use of Trace Eyeblink Classical Conditioning to Assess Hippocampal Dysfunction in a Rat Model of Fetal Alcohol Spectrum Disorders
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The Use of Trace Eyeblink Classical Conditioning to Assess Hippocampal Dysfunction in a Rat Model of Fetal Alcohol Spectrum Disorders

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Fetal alcohol spectrum disorder: report of one case

Yi-Chen Huang1, Hsin-Yu Lo, Wun-Tsong Chaou

  • 1Department of Child Neurology, Puli Christian Hospital, Nanton, Taiwan.

Acta Paediatrica Taiwanica = Taiwan Er Ke Yi Xue Hui Za Zhi
|June 28, 2008
PubMed

Insights

This case highlights fetal alcohol spectrum disorder (FASD) in an Aboriginal boy with developmental delays. Maternal alcohol use during pregnancy is linked to FASD, emphasizing the need for abstinence.

Area of Science:

  • Pediatrics
  • Neurology
  • Genetics

Background:

  • Fetal Alcohol Spectrum Disorder (FASD) is a spectrum of neurodevelopmental disorders caused by prenatal alcohol exposure.
  • Early diagnosis and intervention are crucial for managing FASD.
  • Identifying FASD in diverse populations is important for understanding its prevalence and impact.

Observation:

  • A 7-year-old Aboriginal boy presented with learning difficulties.
  • Physical examination revealed dysmorphic features including microcephaly, a broad nasal bridge, thin upper lip, smooth philtrum, epicanthal folds, and clinodactyly.
  • Brain MRI showed abnormal findings, and the patient exhibited mild intellectual disability and language delay.

Findings:

  • The patient's clinical presentation and maternal history of significant alcohol consumption during pregnancy strongly indicated a diagnosis of Fetal Alcohol Spectrum Disorder (FASD).
  • The constellation of physical, cognitive, and neuroimaging findings aligns with established FASD criteria.
  • This case underscores the potential for FASD to be misdiagnosed as idiopathic developmental delay.

Implications:

  • Prenatal alcohol exposure can lead to a range of developmental issues, including intellectual disability and language deficits.
  • Healthcare providers should consider FASD in children with unexplained developmental delays, even with limited maternal reporting of alcohol use.
  • Promoting complete abstinence from alcohol during pregnancy is vital to prevent FASD and its lifelong consequences.

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