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[The effect of psychoemotional stress on kidney function]
Urologiia I Nefrologiia
|January 1, 1991
Summary
Psychoemotional stress impacts kidney function and elevates middle molecular oligopeptides. Measuring these peptides preoperatively can indicate adequate patient preparation and screen kidney function.
Area of Science:
- Physiology
- Biochemistry
- Nephrology
Context:
- Psychoemotional stress and surgical emergencies induce physiological changes.
- Renal function is often compromised during stress states.
- Biologically active substances, including middle molecular oligopeptides, accumulate during stress.
Purpose:
- To introduce a method for assessing preoperative conditions.
- To evaluate the adequacy of premedication.
- To screen for renal function impairment.
Summary:
- Psychoemotional stress leads to renal functional changes and the accumulation of middle molecular oligopeptides.
- Inadequate premedication for surgery exacerbates these conditions due to substance buildup and reduced kidney function.
- Preoperative measurement of plasma and urine middle molecular oligopeptides can serve as an indirect indicator of premedication adequacy and a renal function screening test.
Impact:
- Provides a novel method for indirect assessment of patient preparedness for surgery.
- Offers a potential screening tool for early detection of renal dysfunction in stressed patients.
- Aids in optimizing surgical outcomes by ensuring adequate patient preparation and monitoring renal status.