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International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure

International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure

Published on: March 12, 2020

Misconceptions, challenges, uncertainty, and progress in guideline recommendations.

Regina Kunz¹, Benjamin Djulbegovic, Holger J Schunemann

¹Basel Institute of Clinical Epidemiology, University Hospital Basel, Basel, Switzerland. rkunz@uhbs.ch

Seminars in Hematology

|June 28, 2008

Summary

The Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system improves clinical practice guidelines by rigorously assessing evidence quality and balancing benefits against harms. This validated approach enhances guideline acceptance and validity for healthcare decision-making.

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Last Updated: Jul 4, 2026

International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure

International Expert Consensus and Recommendations for Neonatal Pneumothorax Ultrasound Diagnosis and Ultrasound-guided Thoracentesis Procedure

Published on: March 12, 2020

Area of Science:

Clinical Practice Guidelines
Health Technology Assessment
Evidence-Based Medicine

Background:

Current clinical practice guideline systems face limitations affecting validity and acceptance.
Improvements in guideline quality over the past decade are acknowledged.

Purpose of the Study:

To introduce and describe the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) system.
To address shortcomings in existing guideline development methodologies.

Main Methods:

Developed a transparent and rigorous methodology for rating evidence quality.
Incorporated explicit balancing of benefits and harms of interventions.
Included explicit acknowledgement of patient values, preferences, and resource utilization.
Defined criteria for strong versus weak recommendations based on patient choice.

Main Results:

The GRADE system provides a structured approach to guideline development.
Recommendations are categorized as strong or weak based on defined criteria.
The system has been tested, refined, and re-evaluated across various settings and questions.
Numerous guideline organizations and medical societies have endorsed and adopted the GRADE system.

Conclusions:

The GRADE system offers a practical and simplified yet comprehensive method for evidence assessment and recommendation grading.
Its widespread adoption by medical societies indicates its utility in improving the quality and acceptance of clinical practice guidelines.