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Phosphorus-31 Magnetic Resonance Spectroscopy: A Tool for Measuring In Vivo Mitochondrial Oxidative Phosphorylation Capacity in Human Skeletal Muscle
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[New therapeutic approaches in mitochondrial fatty acid oxidation disorders]

F Labarthe1

  • 1Service Pédiatrie R, Hôpital Clocheville, CHU Tours, 49 boulevard Béranger, 37044 Tours cedex 1, France. labarthe@med.univ-tours.fr <labarthe@med.univ-tours.fr>

Archives De Pediatrie : Organe Officiel De La Societe Francaise De Pediatrie
|June 28, 2008
PubMed
Abstract

No abstract available in PubMed .

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Electron Transport Chain: Complex I and II01:46

Electron Transport Chain: Complex I and II

The mitochondrial electron transport chain (ETC) is the main energy generation system in the eukaryotic cells. However, mitochondria also produce cytotoxic reactive oxygen species (ROS) due to the large electron flow during oxidative phosphorylation. While Complex I is one of the primary sources of superoxide radicals, ROS production by Complex II is uncommon and may only be observed in cancer cells with mutated complexes.
ROS generation is regulated and maintained at moderate levels necessary...
Overview of Fatty Acid Metabolism01:28

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Lipids also are sources of energy that power cellular processes. Like carbohydrates, lipids are composed of carbon, hydrogen, and oxygen, but these atoms are arranged differently. Most lipids are nonpolar and hydrophobic. Major types include fats and oils, waxes, phospholipids, and steroids.
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