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[Clinical investigation of delayed graft function recovery following renal transplantation]
1Department of Organ Transplantation, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.
Objective:
To investigate the etiology and therapy of delayed graft function (DGF) recovery in renal transplant recipients.
Methods:
The clinical data were retrospectively analyzed in 15 renal recipients with DGF. All the 15 patients received hemodialysis along with pulse treatment against acute rejection (AR), or immunosuppressant adjustment, or in situ retransplantation after the resection of the original transplanted kidney according to different etiological factors.
Results:
Among the 15 patients, 8 developed AR, 5 showed acute renal tubular necrosis (ATN), 1 had grafting-associated renal vein embolism and 1 had acute cyclosporine nephrotoxication. The renal function recovered within 10 to 35 days after transplantation without complication during the follow-up period (0.5-3.0 years).
Conclusion:
DGF is a common complication after kidney transplantation mainly due to the occurrence of AR and ATN. Good prognosis is expected if etiology-oriented therapy is performed properly and promptly.
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