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Arterial Thrombosis in Nephrotic Syndrome due to Minimal Change Glomerulonephritis

K El-Reshaid1, M Kapoor, A Hakim

  • 1Department of Medicine, Faculty of Medicine, Kuwait University, Kuwait.

Saudi Journal of Kidney Diseases and Transplantation : an Official Publication of the Saudi Center for Organ Transplantation, Saudi Arabia
|January 1, 1994
PubMed

We describe our experience with spontaneous arterial thrombosis (AT) in two men with nephrotic syndrome secondary to minimal change glomerulonephritis. Arterial thrombosis developed shortly after a nephrotic crisis in each case. Serum antithrombin III, protein C and protein S levels were normal in both patients. The two cases emphasize the role of defective hemodynamic circulation in the pathogenesis of AT in patients with nephrotic syndrome. Despite their atastrophic presentation, the patients ultimately responded to multiple thrombectomies, volume expanders, anticoagulants and steroid therapy.

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