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Related Concept Videos

Types of Step-Growth Polymers: Polyesters01:20

Types of Step-Growth Polymers: Polyesters

The introduction of polyesters has brought major development to the textile industry. The wrinkle-free behavior of polyester blends has eliminated the need for starching and ironing clothes.
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the polymer...

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Related Experiment Video

Updated: Jul 4, 2026

The Evolution of Silica Nanoparticle-polyester Coatings on Surfaces Exposed to Sunlight
10:27

The Evolution of Silica Nanoparticle-polyester Coatings on Surfaces Exposed to Sunlight

Published on: October 11, 2016

Characterization of surface modified polyester fabric.

Roy Joseph1, R Shelma, A Rajeev

  • 1Biomedical Technology Wing, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Trivandrum 695012, Kerala, India. rjoseph1965@rediffmail.com

Journal of Materials Science. Materials in Medicine
|June 28, 2008
PubMed
Summary
This summary is machine-generated.

Coating polyethylene terephthalate (PET) fabric with polyvinylidine fluoride (PVDF) significantly improved its hemocompatibility, reducing platelet and leukocyte consumption without compromising mechanical properties. This surface modification shows promise for enhanced vascular grafts and heart valve components.

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Area of Science:

  • Biomaterials Science
  • Polymer Chemistry
  • Cardiovascular Engineering

Background:

  • Woven polyethylene terephthalate (PET) fabric is utilized in vascular grafts and prosthetic heart valves.
  • Improving the hemocompatibility and tissue response of PET fabric is crucial for medical device performance.

Purpose of the Study:

  • To enhance the hemocompatibility of PET fabric by coating it with polyvinylidine fluoride (PVDF).
  • To evaluate the impact of PVDF coating on the physical properties, cytotoxicity, and hemocompatibility of PET fabric.

Main Methods:

  • Dip coating technique was employed to apply PVDF onto PET fabric.
  • Physical properties (water permeability, burst strength), cytotoxicity (L929 fibroblast cell lines), and in vitro hemocompatibility (platelet and leukocyte consumption, partial thromboplastin time) were assessed.
  • Endothelial cell proliferation was also studied.

Main Results:

  • PVDF coating was uniform and did not significantly alter water permeability or burst strength.
  • Coated PET demonstrated non-cytotoxicity.
  • Significant improvements in hemocompatibility were observed: 50% reduction in platelet consumption, 24% reduction in leukocyte consumption, and a 60% reduction in partial thromboplastin time (PTT).
  • Endothelial cell proliferation remained unaffected by the surface modification.

Conclusions:

  • PVDF coating effectively enhances the hemocompatibility of PET fabric.
  • The mechanical integrity and endothelial cell compatibility of the PET fabric are preserved.
  • This surface modification presents a viable strategy for improving the performance of cardiovascular implants made from PET fabric.