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Related Concept Videos

Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Bone Marrow Sampling and Transplants01:22

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

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[Tönnis and Kalchschmidt triple pelvic osteotomy].

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[Accompanying diseases and complications in orthopedic surgery].

Der Orthopade·2009
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[Complications after hip operations].

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Related Experiment Video

Updated: Jul 4, 2026

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
13:16

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Published on: December 22, 2015

[Bone allografting].

B-D Katthagen1, A Prub

  • 1Orthopädische Klinik , Klinikum Dortmund gGmbH, Beurhausstrasse 40, 44137, Dortmund. b.d.katthagen@klinikumdo.de

Der Orthopade
|June 28, 2008
PubMed
Summary

Bone allografts are effective for bone reconstruction in orthopedic surgery, simplifying procedures and improving outcomes. These grafts are incorporated and remodeled by the recipient bone, demonstrating good regenerative capacity.

Area of Science:

  • Orthopedic Surgery
  • Biomaterials Science
  • Regenerative Medicine

Context:

  • Bone allografts are utilized in approximately 3% of elective orthopedic operations.
  • Common applications include acetabuloplasty for hip dysplasia and revision total joint arthroplasty.
  • They are also suitable for reconstructing defects from benign bone tumors and tumor-like lesions.

Purpose:

  • To summarize the utility and application of bone allografts in orthopedic surgery.
  • To highlight the regenerative capacity and remodeling of bone allografts post-implantation.
  • To underscore the role of bone allografts in specific orthopedic procedures.

Summary:

  • Bone allografts are crucial for bone reconstruction, with careful donor selection and processing minimizing disease transmission risks.

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Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
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Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model

Published on: August 13, 2017

Use of Human Perivascular Stem Cells for Bone Regeneration
07:05

Use of Human Perivascular Stem Cells for Bone Regeneration

Published on: May 25, 2012

Related Experiment Videos

Last Updated: Jul 4, 2026

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
13:16

Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts

Published on: December 22, 2015

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model
10:31

Surgical Angiogenesis in Porcine Tibial Allotransplantation: A New Large Animal Bone Vascularized Composite Allotransplantation Model

Published on: August 13, 2017

Use of Human Perivascular Stem Cells for Bone Regeneration
07:05

Use of Human Perivascular Stem Cells for Bone Regeneration

Published on: May 25, 2012

  • Despite initial necrosis, allografts are remodeled by recipient bone, showcasing significant regenerative potential.
  • Specific uses include acetabuloplasty, revision arthroplasty, benign bone tumor defect reconstruction, and fibrous dysplasia treatment.

    • Impact:

    • Bone allografts simplify and shorten surgical procedures, leading to improved patient outcomes.
    • They offer a viable solution for complex orthopedic reconstructions, including challenging cases like severe hip dysplasia and bone defects.
    • The successful incorporation and remodeling of allografts demonstrate their effectiveness in bone regeneration.