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Published on: July 13, 2016
[Formation of IQ-compounds in meat and meat products]
1Institut für Lebensmittelchemie der Westfälischen Wilhelms-Universität, Münster.
Abstract:
During meat processing mutagenic imidazoquinolines and imidazoquinoxalines ("IQ-compounds") may be formed by Maillard reaction of reducing sugars, amino acids, and creatine/creatinine. IQ-compounds isolated from low-moisture model systems and meat extract by liquid-liquid-distribution were fractionated on a cation exchanger and separated on an RP phase. After acetylation the separated compounds were identified by gas chromatography/mass spectrometry based on their characteristic mass fragment ions. During heating the model systems at 100 degrees C the formation of IQ-compounds begins and greatly increases by further raising the temperature. In different amounts IQ-compounds could also be detected in commercially available meat extracts.
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