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[Analysis of the circadian rhythm of pain]
1Zentrum der Pharmakologie, Klinikum der J.W. Goethe-Universität, Frankfurt/Main.
Zeitschrift Fur Rheumatologie
|January 1, 1991
Abstract:
An electronic pulp tester was used to study the stimulus threshold in human teeth of 28 healthy volunteers for 1,5-4 days and the duration of local anaesthesia in 55 patients with caries. Rhythm analysis was performed with a non-linear fitting program on an IBM computer (PHARMFIT); in 21 out of the 28 volunteers significant daily rhythms in stimulus threshold could be detected. In the patients the maximum duration of local anaesthesia was after drug application at 2 p.m.