Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Gross Anatomy of the Liver01:17

Gross Anatomy of the Liver

The liver, the largest gland within the human body, is a firm and reddish-brown organ. This wedge-shaped structure weighs approximately 1.5 kg and occupies a significant portion of the right hypochondriac and epigastric regions. It extends more to the right of the body's midline than to the left.
Located under the diaphragm, the liver is almost entirely ensconced within the rib cage, providing it with substantial protection. Except for the superior most bare area, the liver's surface is covered...
Pharmacokinetics in Pediatric Patients: Drug Metabolism01:24

Pharmacokinetics in Pediatric Patients: Drug Metabolism

In pediatric care, understanding the nuances of hepatic drug metabolism is crucial, as it significantly differs from that of adults. This divergence is primarily due to the developmental stage of drug-metabolizing enzymes, which affects how medications are processed in the body. In neonates, for instance, the activity of Phase I enzymes—critical for the initial breakdown of drugs—is markedly reduced, functioning at just 20–40% of the levels seen in adults. This reduction poses a challenge in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Photon-Counting Detector CT in Cardiothoracic Imaging: <i>AJR</i> Expert Panel Narrative Review.

AJR. American journal of roentgenology·2026
Same author

Educational Case: Meningioma.

Academic pathology·2026
Same author

Educational Case: Atypical presentation of primary hyperparathyroidism with brown tumor.

Academic pathology·2026
Same author

Impact of elexacaftor/tezacaftor/ivacaftor on biomarkers of cystic fibrosis hepatobiliary involvement in the PUSH study.

Journal of pediatric gastroenterology and nutrition·2025
Same author

Benign and Malignant Pediatric Liver Masses: Radiologic-Pathologic Update from the Pediatric LI-RADS Working Group.

Radiographics : a review publication of the Radiological Society of North America, Inc·2025
Same author

Photon counting detector computed tomography in pediatric cardiothoracic CT imaging.

Radiology advances·2025

Related Experiment Video

Updated: Jul 4, 2026

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
04:41

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

Pediatric liver: focal masses.

Marilyn J Siegel1, Ellen M Chung, Richard M Conran

  • 1Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 South Kingshighway Boulevard, St. Louis, MO 63110, USA. siegelm@mir.wustl.edu

Magnetic Resonance Imaging Clinics of North America
|July 1, 2008
PubMed
Summary

Magnetic resonance (MR) imaging is key for diagnosing pediatric liver disease. This review covers MR imaging techniques and appearances of focal hepatic lesions in children.

More Related Videos

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach
13:57

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach

Published on: May 23, 2025

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

Related Experiment Videos

Last Updated: Jul 4, 2026

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy
04:41

Application of the En Bloc Concept Combined with Anatomic Resection in Laparoscopic Hepatectomy

Published on: March 10, 2023

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach
13:57

Laparoscopic Anatomical Liver Segment VII Resection with Liver Parenchymal Transection Following a Priority Approach

Published on: May 23, 2025

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis
05:56

Implementation of Non-invasive Point of Care Transient Elastography for Evaluation of Liver Disease in Pediatric Populations with Cystic Fibrosis

Published on: August 29, 2025

Area of Science:

  • Pediatric Radiology
  • Hepatology
  • Medical Imaging

Background:

  • Liver disease in children requires accurate diagnostic imaging.
  • Magnetic resonance (MR) imaging has advanced significantly, enhancing lesion detection and characterization.
  • Focal hepatic lesions are common in pediatric populations.

Purpose of the Study:

  • To review the MR imaging appearances of focal hepatic lesions in children.
  • To discuss techniques for performing hepatic MR imaging in pediatric patients.
  • To provide a guide for radiologists evaluating pediatric liver abnormalities.

Main Methods:

  • Review of current literature on pediatric hepatic MR imaging.
  • Discussion of established and novel MR imaging techniques.
  • Compilation of characteristic MR imaging findings for various focal hepatic lesions.

Main Results:

  • MR imaging offers superior detection, characterization, and staging of hepatic lesions compared to other modalities.
  • Specific MR imaging features help differentiate between various benign and malignant focal hepatic lesions.
  • Optimized MR imaging protocols improve diagnostic accuracy in pediatric liver disease.

Conclusions:

  • MR imaging is an essential tool for evaluating focal hepatic lesions in children.
  • Familiarity with MR imaging techniques and lesion appearances is crucial for effective diagnosis.
  • Advanced MR imaging facilitates comprehensive assessment and management planning for pediatric liver conditions.