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Related Experiment Video

Updated: Jul 4, 2026

Manipulating the Murine Lacrimal Gland

Manipulating the Murine Lacrimal Gland

Published on: November 18, 2014

Proboscis-like Brunner's gland hyperplasia.

Chen-Wang Chang¹, Wen-Hsiung Chang, Shou-Chuan Shih

¹Division of Gastroenterology, Department of Internal Medicine, Mackay Memorial Hospital, No. 92, Sec. 2, Chung-Shan N. Rd., Taipei, Taiwan.

American Journal of Surgery

|July 1, 2008

Summary

Brunner's gland hyperplasia is a benign duodenal lesion found incidentally during upper gastrointestinal endoscopies. This case highlights a large, asymptomatic lesion successfully treated with surgery.

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Sectioning Mammary Gland Whole Mounts for Lesion Identification

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Published on: July 24, 2017

Area of Science:

Gastroenterology
Surgical Pathology

Background:

Brunner's gland hyperplasia (BGH) is a common benign duodenal lesion.
It is incidentally discovered in approximately 2% of upper gastrointestinal endoscopies.

Observation:

A 34-year-old asymptomatic female presented with a large, 12-cm duodenal lesion.
The lesion had a distinctive 'elephant's proboscis' morphology.

Findings:

Surgical excision confirmed the lesion as Brunner's gland hyperplasia.
This represents a rare, large presentation of an otherwise typically incidental finding.

Implications:

Surgical intervention can be curative for symptomatic or large BGH.
Endoscopic and surgical management strategies for BGH require careful consideration based on size and presentation.