X-ray phase radiography and tomography of soft tissue using grating interferometry
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Updated: Jul 4, 2026

Non-invasive 3D-Visualization with Sub-micron Resolution Using Synchrotron-X-ray-tomography
Published on: May 27, 2008
Timm Weitkamp1, Christian David, Oliver Bunk
1European Synchrotron Radiation Facility, 6 rue Jules Horowitz, BP 220, 38043 Grenoble, France. weitkamp@esrf.fr
Abstract:
X-ray phase and absorption radiographs and tomograms of the heart of a rat were taken with an X-ray grating interferometer with monochromatic synchrotron radiation at a photon energy of 17.5 keV. The phase images show largely superior quality with respect to the absorption images taken with the same dose, particularly much better contrast and contrast-to-noise ratio. Different tissues can clearly be distinguished. The results demonstrate the potential of grating interferometry for two- and three-dimensional X-ray imaging of biological soft tissue in an aqueous environment.
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