Simultaneous sizing and preoperative risk stratification for thoracic endovascular aneurysm repair: role of gated
Felix J V Schlösser1, Hamid R Mojibian, Alan Dardik
1Section of Vascular Surgery, Yale University, New Haven, Connecticut 06510, USA.
Insights
Electrocardiogram-gated CT angiography enables simultaneous assessment of thoracic aortic aneurysms and cardiac structures. This technique provides diagnostic image quality for both thoracic aorta pathology and coronary artery disease.
Area of Science:
- Cardiovascular Imaging
- Thoracic Radiology
Background:
- Thoracic aortic aneurysms (TAA) share risk factors with other cardiovascular diseases.
- Coronary artery disease (CAD) is highly prevalent in TAA patients (30-70%).
- Assessing cardiac pathology preoperatively minimizes risk and improves patient selection.
Purpose of the Study:
- To investigate the feasibility of simultaneously assessing thoracic aortic pathology and cardiac structures using ECG-gated 64-slice CT angiography.
- To evaluate the capability of this technique in visualizing coronary arteries, cardiac function, and valve characteristics.
Main Methods:
- Review of ECG-gated 64-detector row CT scans from 11 patients with thoracic aortic pathology.
- Assessment of images for coronary artery disease, calcifications, cardiac function, and valve characteristics.
- Simultaneous measurement of thoracic aortic pathology using the same CT scan.
Main Results:
- Successful assessment of all images for calcium scores, coronary artery stenoses, and anomalies.
- Diagnostic image quality achieved for cardiac function, valve anatomy, and thoracic aortic disease.
- Comprehensive evaluation of interventricular septal wall thickness, myocardial scar, ejection fraction, and muscle mass.
Conclusions:
- ECG-gated CT angiography allows dynamic imaging of the thoracic aorta and cardiac structures in a single scan.
- This technique is feasible for assessing thoracic aorta pathology, cardiac disease, and extracardiac findings.
- This approach may become a primary imaging modality for preoperative cardiac risk stratification in TAA patients.
Objectives:
Risk factors are similar for the development of both thoracic aortic aneurysms (TAA) and other cardiovascular diseases. Coronary artery disease is highly prevalent in patients with TAA, with a reported prevalence of 30% to 70%. Knowledge of the underlying cardiac pathology can minimize perioperative risk and improve patient selection. This study investigated the feasibility of simultaneous assessment of thoracic aortic pathology and cardiac structures and function, including the coronary arteries, using electrocardiogram-gated 64-slice computed tomography (CT) angiography.
Methods:
ECG-gated 64-detector row CT examinations of 11 patients (8 men, 3 women; mean age, 67 +/- 16; range, 41-83 years) with thoracic aortic pathology, including aneurysms and dissections, were reviewed. Images were assessed for coronary artery disease, calcifications, cardiac function, and valve characteristics. Simultaneous assessment and measurements of thoracic aortic pathology were performed with the same scan.
Results:
All images of the patients could be successfully assessed for calcium scores, coronary artery stenoses, coronary artery anomalies, interventricular septal wall thickness, myocardial scar, left ventricular ejection fraction, muscle mass, and aortic and mitral valve calcification, mobility, and valve anatomy. Diagnostic image quality was also achieved in all patients for the underlying thoracic aortic disease.
Conclusion:
This study introduces the feasibility of dynamic imaging of the thoracic aorta and cardiac structures and function, including the coronary arteries, with just one CT scan. The images could be successfully assessed for thoracic aorta pathology, cardiac disease, and extracardiac pathology. With further developments of CT scanners-and more detailed insight in the prognosis of patients based on ECG-gated CTA findings-this new technique may become the initial imaging modality for preoperative cardiac risk stratification in patients with TAAs or dissections.
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