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Updated: Jul 4, 2026

Application of Bedside Lower Extremity Rehabilitation Robots in Stroke Rehabilitation: A Randomized Controlled Trial
Published on: November 28, 2025
Automatic synchronization of functional electrical stimulation and robotic assisted treadmill training
1Department of Veterans Affairs Medical Center, Cleveland, OH 44106, USA. markdohring@ieee.org
This study developed automatic synchronization for functional electrical stimulation (FES-IM) and the Lokomat robotic gait orthosis, improving consistency and accuracy for stroke survivor gait training.
Area of Science:
- Biomedical Engineering
- Rehabilitation Technology
- Neuroscience
Background:
- Stroke survivors often experience gait deficits, impacting mobility and quality of life.
- Current gait training technologies like functional electrical stimulation (FES-IM) and robotic exoskeletons (Lokomat) show promise but require precise synchronization.
- Manual synchronization between FES-IM and the Lokomat can be inconsistent, limiting training effectiveness.
Purpose of the Study:
- To develop and validate a system for automatic synchronization of intramuscular functional electrical stimulation (FES-IM) with the Lokomat robotic gait orthosis.
- To enhance the precision and reliability of gait training for stroke survivors.
Main Methods:
- A novel hardware and software system was engineered to enable automatic synchronization.
- Bench tests were conducted to evaluate the feasibility, reliability, and accuracy of the automatic synchronization system.
- Performance was compared against manually triggered FES-IM.
Main Results:
- Automatic synchronization of FES-IM to the Lokomat gait cycle was demonstrated as feasible and reliable.
- The system achieved a 10-fold smaller standard deviation in latency compared to manual triggering.
- Stimulation was timed with 2.5% accuracy within the gait cycle, with no early or missed stimulations across 634 strides.
Conclusions:
- Automatic synchronization of FES-IM and Lokomat is a reliable and accurate method for gait training.
- This technology offers improved consistency over manual triggering, potentially enhancing rehabilitation outcomes for stroke survivors.
- The developed system represents a significant advancement in integrated neurorehabilitation technologies.
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