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Bioreactor Controls-I01:28

Bioreactor Controls-I

Maintaining optimal conditions within fermenters is essential for maximizing microbial productivity and ensuring process efficiency. This lesson focuses on key parameters—temperature, foam, pH, carbon dioxide, oxygen, and pressure—and their precise measurement and control strategies in fermentation systems.Temperature ControlTemperature regulation is critical due to the exothermic nature of many fermentation processes. In small laboratory fermenters, temperature is commonly monitored using...

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Related Experiment Video

Updated: Jul 4, 2026

Simulation of a Scaled Assembly Process with Collaboration of a Robotic Arm and Monitoring through a Vision System for Quality Control
05:47

Simulation of a Scaled Assembly Process with Collaboration of a Robotic Arm and Monitoring through a Vision System for Quality Control

Published on: August 29, 2025

'Stoffenmanager', a web-based control banding tool using an exposure process model.

Hans Marquart1, Henri Heussen, Maaike Le Feber

  • 1TNO Quality of Life, Food & Chemical Risk Analysis, Utrechtseweg 48, PO Box 350, 3700 AJ Zeist, The Netherlands. hans.marquart@tno.nl

The Annals of Occupational Hygiene
|July 1, 2008
PubMed
Summary
This summary is machine-generated.

A new internet-based tool, Stoffenmanager, aids small and medium-sized companies in managing hazardous substances. Its risk banding scheme effectively predicts exposure levels, improving workplace safety policies.

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Area of Science:

  • Occupational Health and Safety
  • Environmental Health
  • Risk Assessment

Background:

  • Small and medium-sized enterprises (SMEs) often lack resources for comprehensive hazardous substance management.
  • Existing policies require reinforcement regarding safe handling of hazardous chemicals in the workplace.
  • Development of accessible tools is crucial for improving occupational safety in SMEs.

Purpose of the Study:

  • To develop an internet-based tool, Stoffenmanager, to assist SMEs in handling hazardous substances.
  • To implement a risk banding scheme integrating hazard and exposure assessments.
  • To provide practical solutions for risk reduction and workplace instruction.

Main Methods:

  • Development of Stoffenmanager, an internet-based tool for hazardous substance management.
  • Integration of a hazard banding scheme (similar to COSHH Essentials) and a modified exposure model.
  • Calculation of exposure scores based on emission, transmission, and immission determinants.
  • Comparison of calculated exposure scores with measured exposure levels.

Main Results:

  • The Stoffenmanager tool incorporates a risk banding scheme for prioritizing tasks involving hazardous substances.
  • Exposure scores derived from the tool showed good correlation with measured exposure levels.
  • The modified exposure model is user-friendly for non-expert users in SMEs.
  • The tool facilitates the creation of action plans and workplace instruction cards.

Conclusions:

  • The Stoffenmanager is an effective tool for SMEs to manage hazardous substances and improve working conditions.
  • The risk banding approach provides a practical method for assessing and controlling chemical risks.
  • The tool's validated exposure model supports informed decision-making for risk mitigation.
  • Further development of practical tools for SMEs has been stimulated by this initiative.