Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Attention-Deficit/Hyperactivity Disorder01:30

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings.
Alzheimer Disease l: Introduction01:29

Alzheimer Disease l: Introduction

Alzheimer disease is a chronic, progressive, and irreversible neurodegenerative disorder and the most common cause of dementia in older adults. It leads to gradual neuronal loss, causing cognitive decline, behavioral changes, and loss of functional independence.Risk Factors and EtiologyThe disease is multifactorial. Age is the strongest risk factor, with prevalence doubling every 5 years after age 65. Genetic factors include mutations in genes such as APP, PSEN1, and PSEN2, which are associated...
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
Dementia l: Introduction01:22

Dementia l: Introduction

Dementia is an acquired, progressive syndrome characterized by a decline in multiple cognitive domains severe enough to impair daily functioning and reduce independence. Although memory loss is a central feature, the diagnosis requires additional deficits involving language, executive function, visuospatial skills, judgment, calculation, or abstract reasoning. These cognitive impairments reflect underlying neurodegenerative or vascular processes that gradually disrupt neuronal networks...
Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Grasping the big picture: impact analysis of screening tools for timely referral for device-aided therapies.

Journal of neural transmission (Vienna, Austria : 1996)·2024
Same author

Should continuous dopaminergic stimulation be a standard of care in advanced Parkinson's disease?

Journal of neural transmission (Vienna, Austria : 1996)·2023
Same author

Cortical Brain Perfusion and Cognitive Event Related Potentials in Patients with Psychomotor Retardation in Late Onset Depression.

Psychiatria Danubina·2022
Same author

Management of dystonia in Europe: a survey of the European network for the study of the dystonia syndromes.

European journal of neurology·2016
Same author

Silencing of the cell cycle checkpoint gene 14-3-3σ in basal cell carcinomas correlates with reduced expression of IKK-α.

Journal of the European Academy of Dermatology and Venereology : JEADV·2013
Same author

Cognition in late onset depression.

Psychiatry research·2013
Same journal

Transforming women's mental health with large language models: Opportunities and challenges in digital interventions.

Psychiatria Danubina·2026
Same journal

Impact of cognitive-behavioral therapy for early postpartum depression among primiparous women.

Psychiatria Danubina·2026
Same journal

The impact of housing conditions and nutritional quality on the psycho-emotional state of young internally displaced persons during the Russo-Ukrainian war: The role of secondary stressors.

Psychiatria Danubina·2026
Same journal

Beyond the pandemic: The case for removing obsolete COVID-19 signage in clinical spaces.

Psychiatria Danubina·2026
Same journal

Revamping mariner's mental health using quantum computing techniques.

Psychiatria Danubina·2026
Same journal

Integrating Pilates and myofunctional therapy for better sleep and psychosocial outcomes in obesity-associated obstructive sleep apnea.

Psychiatria Danubina·2026
See all related articles

Related Experiment Video

Updated: Jul 4, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
04:33

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Executive dysfunction in late-onset depression.

Marko Pisljar1, Z Pirtosek, G Repovs

  • 1Psychiatric Hospital Idrija, Pot sv. Antona 49, SI-5280 Idrija, Slovenia. marko.pisljar@amis.net

Psychiatria Danubina
|July 1, 2008
PubMed
Summary
This summary is machine-generated.

Elderly individuals with late-onset depression exhibit executive dysfunction, impacting cognitive processes like planning and attention. This study confirms these executive function changes in older adults with depression.

More Related Videos

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
08:42

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Published on: May 19, 2015

Related Experiment Videos

Last Updated: Jul 4, 2026

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder
04:33

Association Between Sleep Quality and Cognitive Symptoms in Patients with Major Depressive Disorder

Published on: April 26, 2024

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression
08:42

Design and Implementation of an fMRI Study Examining Thought Suppression in Young Women with, and At-risk, for Depression

Published on: May 19, 2015

Area of Science:

  • Geriatric Psychiatry
  • Neuropsychology
  • Cognitive Science

Background:

  • Late-onset depression in the elderly often co-occurs with cognitive impairment.
  • Executive dysfunction, including issues with planning and organization, is a noted feature of geriatric depression.
  • Executive dysfunction is linked to relapse and persistent symptoms in older adults with major depression.

Purpose of the Study:

  • To assess executive functioning deficits in elderly patients diagnosed with late-onset depression.
  • To compare the executive performance of depressed older adults with age-matched healthy controls.

Main Methods:

  • Utilized the computer version of the Stroop Color-Word test for detailed reaction time analysis.
  • Assessed executive functioning in patients with late-onset depression and age-matched healthy volunteers.
  • Measured depression severity using the Hamilton Depression Rating Scale and Geriatric Depression Scale.

Main Results:

  • Preliminary findings indicate increased absolute reaction times in the Stroop test for patients with late-onset depression.
  • Observed significant differences in interference effects, suggesting altered attentional processes in depressed elderly individuals.
  • Confirmed characteristic changes in executive functions among elderly patients with depression.

Conclusions:

  • Preliminary results support the presence of executive function changes in elderly individuals with late-onset depression.
  • The study highlights differences in cognitive processing, specifically attention, between depressed older adults and healthy controls.
  • These findings underscore the cognitive impact of depression in the geriatric population.