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Updated: Jul 4, 2026

Continuous Liquid-Liquid Extraction of Medium-Chain Fatty Acids from Fermentation Broth Using Hollow-Fiber Membranes
Published on: August 9, 2024
Acetone-butanol-ethanol (ABE) production in a novel hollow fiber fermentor-extractor
1Department of Chemistry and Chemical Engineering, Stevens Institute of Technology, Castle Point, Hoboken, New Jersey 07030, USA.
Abstract:
Acetone-butanol-ethanol (ABE) production by immobilized C. acetobutylicum cells is studied in a novel microporous hollow fiber based tubular fermentor-extractor. The solvent 2-ethyl-l-hexanol is used for in situ dispersion-free extraction of products. A mathematical model for simultaneous fermentation and extraction of the products has been investigated. The predicted as well as experimental data follow the same trend. The experimentally observed value of total solvent productivity increased by more than 40% as a result of in situ solvent extraction.
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