Related Experiment Video
Updated: Jul 4, 2026

Isolation of Cells with Morphological and Spatial Information from Oral Submucous Fibrosis Samples by Laser Capture Microdissection
Published on: August 11, 2023
[Rosai-Dorfman's disease: a propos of an interesting case study]
Gustavo Córdova Ramos1, Victoriano Machin González, Som My Benítez Tang
1Servicio de Otorrinolaringología. Hospital Hermanos Ameijeiras. La Habana. Cuba. orl@hha.sld.cu
Abstract:
We present a case with involvement of both nostrils by the Rosai-Dorfman's disease. Physical examination revealed tumorous lesions totally occupying the right nostril and partially the left one. The presence of proliferation of histiocytes was proved by the histological test, several of them full of non-disintegrated lymphoid nuclei, i.e. emperipolesis, the basic histological characteristic in Rosai-Dorfman's disease. The patient underwent surgical treatment with a combined approach by means of lateral rhinotomy and endoscopic nasal resection using a microdebrider.
