Related Experiment Video
Updated: Jul 4, 2026

Novel Production Protocol for Small-scale Manufacture of Probiotic Fermented Foods
Published on: September 10, 2016
[Safety assessment of starters culture bacteria in fermented milk in China]
Jin Xu1, Weixing Yan, Baolan Yang
1Institute of Nutrition and Food Safety, Chinese Center for Control and Prevention, Beijing 100021, China.
Abstract:
In this study, we analysised the safety of 137 strains of starters culture bacteria in fermented milk between 2000 and 2006 in China. The study was designed to evaluate the acute oral toxicity of 137 strains to mice, and 31 of 137 strains for Minimum inhibitory concentrations (MIC) of 20 kinds of antibiotics by broth micro-dilution method. The result indicated that except a strain of Lactobacillus rhamnosus, other probiotics were non-pathogenic and safe for human consumption. 31 strains of probiotics were sensitive to Ampicillin, Penicillin, Imipenem, Gentamicine, Amoxicillin, Amoxicillin/clavulanic acid, Gatifloxacin, Erythromycin, Clindamycin, and were resistant to Nalidixic acid, Vancomycine, Fosfomycin.
Related Concept Videos
Microbes in Food Production
Microbes in the Production of Fermented Foods
Microbes in Beverage Production
Production of Organic Acids
Microbial Spoilage of Food
Scale-Up Processes

