[Primary artificial lens implantation in young children with the primary hyperplastic vitreous body]

Area of Science:

• Ophthalmology
• Pediatric Surgery
• Vitreoretinal Surgery

Background:

• Primary persistent hyperplastic vitreous body (PHPV) is a congenital condition affecting vision.
• Surgical intervention for PHPV is often complicated by severe ocular abnormalities.
• Limited data exists on the long-term functional outcomes of early intraocular lens (IOL) implantation in pediatric PHPV cases.

Purpose of the Study:

• To evaluate the functional results of early primary intraocular lens (IOL) implantation in children diagnosed with primary persistent hyperplastic vitreous body (PHPV).
• To compare outcomes between a cohort undergoing IOL implantation and a control group without IOLs.

Main Methods:

• A comparative study involving 30 children (30 eyes) aged 2 months to 5 years with PHPV.
• A study group of 12 children received early primary IOL implantation (flexible lenses).
• A control group of 18 children underwent surgery without IOL implantation.

Main Results:

• The study group with IOL implantation demonstrated satisfactory functional results.
• Early IOL implantation yielded positive outcomes despite pre-existing severe retinal and optic nerve changes.
• Postoperative follow-up ranged from 6 to 40 months, indicating sustained benefits.

Conclusions:

• Early primary IOL implantation is a viable and effective surgical strategy for managing primary persistent hyperplastic vitreous body in children.
• This approach can lead to favorable functional outcomes, even in complex cases with significant ocular pathology.
• The findings support the consideration of early IOL implantation to improve visual prognosis in pediatric PHPV.