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[Chemical constituents of the spores of Ganoderma lucidum]
Xiao-qi Zhang1, Guo-liang Pang, Yan Cheng
1Institute of Traditional Chinese Medicine and Natural Products, Jinan University, Guangzhou 510632, China.
Objective:
To study the chemical constituents of the sporoderm-broken spores of Ganoderma lucidum.
Methods:
Chemical constituents were isolated and purified by silica gel and Sephadex LH-20 column chromatography. The structures were identified by means of physicochemical and spectral data.
Results:
From the ethyl acetate extract of the material, eight compounds were isolated. Their structures were identified as ganoderic acid A (I), methyl ganoderate A (II), methyl ganoderate B (III), ganoderic acid C2 (IV), ganoderic acid G(V), ergosta-7,22-diene-3beta, 5alpha, 6beta-triol (VI), ergosterol peroxide (VII) and ergosta-7,22-diene-3beta-yl pentadecanoate (VIII), respectively.
Conclusion:
Compounds II, III, VII and VIII are isolated from the spores of G. lucidum for the first time.
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