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[Studies on chemical constituents of Caragana spinifera]
Yan-Ru Deng1, Tao Wang, Yong-Zhi He
1Tianjin Key lab of Chemistry and Analysis of Chinese Materia Medica, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China. dyanru@sina.com
Objective:
To study the chemical constituents of the whole plant Caragana spinifera.
Method:
The chemical constituents were isolated and repeatedly purified on silica gel column. The structures were elucidated by the NMR spectra and physico-chemical properties.
Result:
Six compounds were isolated and identified as (6aR, 11aR) 4,9-dimethoxy-3-hydroxypterocarpan, (6aR,11aR)-4, 9-dihydroxy-3- methoxypterocarpan (melilotocarpane B), 5, 4'-dihydroxy-7-methoxyisoflavone, 7-hydroxy4'-methoxyisoflavone, 6, 7-dihydroxy4'-methoxyisoflavone, beta-sitosterol respectively.
Conclusion:
All compounds were isolated from the plant for the first time.
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