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Microbial Control and Monitoring Strategies for Cleanroom Environments and Cellular Therapies
Published on: March 17, 2023
[Progress of environmental monitoring and biological containment system on genetically engineered microorganisms]
1Laboratory of Molecular Toxicology, State Key Laboratory for Integrated Management of Pest Insects and Rodents, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
Abstract:
With the development of biological technology, many genetically engineered microorganisms (GEMs) for special purposes have been constructed and developed, but their practical applications in the field are still limited because GEMs may cause new environmental contaminations. To minimize the potential risks, the organisms released to environment need to be monitored and restricted for their distribution. In the laboratory conditions, the GEMs can be wiped off when required using some new biological technologies. The recent progress of research on the monitoring methods and active biological containment system for GEMs were reviewed in this paper.
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