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Updated: Jul 4, 2026

Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
ENT manifestations of gastroesophageal reflux
Desiderio Passàli1, Giuseppe Caruso, Francesco Maria Passàli
1Ear, Nose, and Throat Clinic, Policlinico Le Scotte, University of Siena, 53100, Siena, Italy. passali@unisi.it
Abstract:
Gastroesophageal reflux (GER) has been associated with a variety of supraesophageal symptoms or diseases, including chronic cough, laryngeal disorders, rhinosinusitis, otitis media, and oral cavity lesions. In this article, we review the relationship between GER and ear, nose, and throat (ENT) symptoms. Data in the published literature are frequently conflicting. Only a few studies are controlled, and an evidence-based approach provides weak support for a causal association between GER and ENT manifestations. The GER diagnostic method should be standardized utilizing new parameters, and the definition and diagnostic accuracy of ENT pathologies also must be better specified. A firm connection remains controversial, and further randomized trials are needed.
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