[Study on anti-diabetes active fraction and constituents from Potentilla chinesis]
Chuan Zhao1, Wei Qiao, Yan-Wen Zhang
1School of Pharmaceutical Sciences, Tianjin Medical University, Tianjin 300070, China.
Abstract
Objective:
To study the active fraction and constituents from Potentilla chinesis.
Method:
Tested fractions were obtained by different solvent-partition from 95% ethanol-extracts of P. chinesis, and tested compound was isolated by repeated chromatography. Anti-diabetes experiment was taken by using alloxan-induced diabetic mice.
Result:
The fraction F and the tested compound revealed obvious difference comparing with the control group (P <0.01).
Conclusion:
Fraction F and potentilla flavone revealed the significant hypoglycemic effect in alloxan-induced diabetic mice.