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Related Concept Videos

Mitral Stenosis III: Medical Management01:26

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Cardiac Catheterization I: Pre-Procedure Overview01:28

Cardiac Catheterization I: Pre-Procedure Overview

Cardiac catheterization is an invasive diagnostic technique used to identify and evaluate structural and functional diseases of the heart and major blood vessels. This technique diagnoses congenital heart disease, coronary artery disease, valvular heart disease, and coronary spasms and assesses ventricular function. It helps guide treatment decisions, including the need for revascularization procedures like percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG) and...
Heart Failure VI: Adjunct Therapies01:22

Heart Failure VI: Adjunct Therapies

Additional therapies for treating patients with heart failure (HF) may include procedural interventions, supplemental oxygen, the management of sleep disorders, and nutritional therapy.Procedural InterventionsImplantable Cardioverter-Defibrillator: For patients at risk of life-threatening arrhythmias due to severe left ventricular dysfunction, an Implantable Cardioverter-Defibrillator (ICD) can detect and terminate these arrhythmias, preventing sudden cardiac death and improving survival rates.

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Related Experiment Video

Updated: Jul 4, 2026

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model
05:31

Transcatheter Pulmonary Valve Replacement from Autologous Pericardium with a Self-Expandable Nitinol Stent in an Adult Sheep Model

Published on: June 8, 2022

[Percutaneous transcatheter valve therapy].

Paul T L Chiam1, Raquel del Valle-Fernández, Carlos E Ruiz

  • 1Department of Cardiac and Vascular Interventional Services, Lenox Hill Heart and Vascular Institute of New York, New York, USA.

Revista Espanola De Cardiologia
|August 6, 2008
PubMed
Summary

Percutaneous transcatheter valve therapy is rapidly evolving for aortic stenosis and mitral regurgitation. Transcatheter aortic valve replacement shows promise as a viable option for selected patients, with ongoing advancements in mitral valve repair and replacement technologies.

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Published on: January 20, 2022

Area of Science:

  • Cardiovascular Medicine
  • Interventional Cardiology
  • Biomedical Engineering

Context:

  • Aortic stenosis (AS) and mitral regurgitation (MR) are prevalent valvular heart diseases in developed nations.
  • Current standard treatment involves surgical valve replacement or repair.
  • Transcatheter valve therapies have emerged as rapidly advancing alternatives.

Purpose:

  • To review the current status and future directions of percutaneous transcatheter valve therapies for AS and MR.
  • To highlight the progress and challenges in developing percutaneous aortic valve replacement (PAVR) and percutaneous mitral valve (MV) repair/replacement.

Summary:

  • Percutaneous aortic valve replacement (PAVR) is nearing clinical viability for select patients, with ongoing development of improved, repositionable, and retrievable devices.
  • Percutaneous mitral valve repair is more complex due to diverse etiologies of MR, with current technologies suited for specific patient groups.
  • Future advancements include nanotechnology and tissue engineering for AS and MV treatment, with percutaneous MV replacement anticipated as a key development.

Impact:

  • PAVR is expected to become a significant treatment option for severe aortic stenosis in the near future.
  • Advances in percutaneous mitral valve repair and replacement hold potential for improved patient outcomes and less invasive treatment strategies.
  • The integration of novel materials and technologies will drive the evolution of transcatheter valve therapies.