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An In vitro Co-infection Model to Study Plasmodium falciparum-HIV-1 Interactions in Human Primary Monocyte-derived Immune Cells
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[Immigration and HIV Infection. An approximation to parasitic and viral infections]

José Manuel Ramos Rincón1, Zuriñe Zubero Sulibarría, Javier Ena Muñoz

  • 1Unidad de Enfermedades, Hospital General Universitario de Elche, Elche, Alicante, España. jramosrincon@yahoo.es

Enfermedades Infecciosas Y Microbiologia Clinica
|December 17, 2008
PubMed

Insights

Opportunistic parasitic infections cause most HIV deaths in developing nations, unlike industrialized countries. This review examines parasitic and viral infections in HIV patients to aid understanding of this vulnerable group.

Area of Science:

  • Infectious Diseases
  • Virology
  • Parasitology

Context:

  • Highly-active antiretroviral therapy (HAART) reduces opportunistic infections in industrialized nations.
  • Opportunistic parasitic infections are a primary cause of HIV mortality in developing countries.
  • HIV-positive immigrants and travelers to low-income countries are also at risk.

Purpose:

  • To review the characteristics of parasitic and viral infections in HIV-infected individuals.
  • To enhance understanding of infection risks in vulnerable populations, including immigrants and travelers.
  • To highlight the disparity in HIV-related mortality due to opportunistic infections between developed and developing countries.

Summary:

  • While HAART is effective in industrialized countries, parasitic infections remain a major cause of death in developing nations.
  • HIV-positive immigrants and travelers face risks from both parasitic and viral infections (herpesvirus, papillomavirus, polyomavirus).
  • These viral infections are often linked to risk behaviors and commercial sex.

Impact:

  • Improved understanding of parasitic and viral infections in HIV patients can lead to better targeted interventions.
  • Addresses the critical health disparities in HIV management between different global regions.
  • Provides insights for healthcare providers managing HIV-infected immigrants and travelers.

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