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Updated: Jul 4, 2026

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease
Published on: July 24, 2019
A comparison of Parkinson's disease symptoms and self-reported functioning and well being
K E Lyons1, R Pahwa, A I Troster
1University of Kansas Medical Center, Department of Neurology, 3901 Rainbow Blvd., Kansas City, KS 66160-7314 U.S.A.
Abstract:
This study was designed to determine if the presence of tremor, rigidity, bradykinesia and postural instability and gait abnormalities differentially influence Parkinson's disease patients' ratings of quality of life as measured by the Parkinson's Disease Questionnaire (PDQ-39). A regression analysis indicated that the presence of postural instability and gait abnormalities and bradykinesia were strongly predictive of PDQ-39 quality of life scores. The presence of tremor and rigidity had little effect on patients' ratings of quality of life.
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