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[Optic disc drusen].

M Schargus1, E Gramer

  • 1Universitätsaugenklinik Würzburg, Josef-Schneider-Strasse 11, 97080, Würzburg, Deutschland. Marc.Schargus@gmx.de

Der Ophthalmologe : Zeitschrift Der Deutschen Ophthalmologischen Gesellschaft
|July 2, 2008
PubMed
Summary
This summary is machine-generated.

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Optic disc drusen (ODD) can cause progressive vision loss. Lowering intraocular pressure (IOP) may slow visual field loss progression in ODD patients.

Area of Science:

  • Ophthalmology and Optic Neuropathy
  • Genetics and Hereditary Conditions

Context:

  • Optic disc drusen (ODD) are a progressive, often bilateral optic neuropathy with a genetic basis.
  • ODD can be initially asymptomatic but frequently leads to visual field loss (VFL).

Purpose:

  • To summarize current knowledge on the epidemiology, pathogenesis, clinical presentation, diagnostics, and therapy of optic disc drusen.
  • To highlight the association between ODD, visual field loss, and potential therapeutic interventions.

Summary:

  • 64% of patients with ODD experienced visual field loss, with progression linked to age.
  • Vascular complications like anterior ischemic optic neuropathy (AION) are common.
  • A pilot study indicated that intraocular pressure (IOP)-lowering therapy may reduce VFL progression.

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Impact:

  • ODD can lead to significant visual impairment, impacting daily activities like driving.
  • Early diagnosis and management, including IOP reduction, are crucial for preserving vision.
  • This review provides a comprehensive overview for clinicians and researchers in the field.