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Updated: Jul 4, 2026
An In Vitro Approach to Photodynamic Therapy
Published on: August 17, 2018
[Photodynamic therapy in vulvar intraepithelial neoplasia]
Anita Olejek1, Iwona Kozak-Darmas, Tomasz Biniszkiewicz
1Katedra i Oddział Kliniczny Ginekologii, Połoznictwa i Ginekologii Onkologicznej SIUM w Bytomiu, Bytom. anitaolejek@wp.pl
Introduction:
Vulvar intraepithelial neoplasia may lead to vulvar cancer. Vulvar cancer is a rare (accounting for about 2,5-5% of all malignant neoplasms), female genital organs cancer. Photodynamic therapy is a new treatment for a wide variety of malignancies and premalignant dysplasias. We wanted to examine the effectiveness of photodynamic therapy (PDT) on vulvar intraepithelial neoplasia (VIN).
Design:
The aim of the study was to analyze the effectiveness of photodynamic therapy (PDT) on vulvar intraepithelial neoplasia (VIN).
Material And Methods:
We have analyzed 20 women with VIN, who were treated in our center - Clinic of Vulvar Diseases. All these women had photodynamic diagnosis (PDD), photodynamic therapy followed (PDT), with 5% ALA applied to the entire vulva.
Conclusions:
We have noted the reduction of subjective complaints, but the histopathological improvement was observed in fewer degree.
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