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Related Concept Videos

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features01:24

Chronic Obstructive Pulmonary Disease III: Chronic Bronchitis Features

Chronic bronchitis is a key phenotype of chronic obstructive pulmonary disease (COPD), characterized by airway-centered inflammation and mucus overproduction. It develops from long-term exposure to harmful particles or gases, most commonly cigarette smoke, which triggers a persistent inflammatory response.Cellular and Structural ChangesInflammation initially affects the large bronchi and later the smaller airways, with infiltration by immune cells, including neutrophils, macrophages, and...
Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations01:19

Chronic Obstructive Pulmonary Disease IV: Clinical Manifestations

Chronic Obstructive Pulmonary Disease, or COPD, is a long-term condition marked by persistent and only partially reversible airflow limitation. It involves two overlapping conditions—chronic bronchitis and emphysema—which often co-appear but differ in dominant symptoms and underlying mechanisms.Chronic Bronchitis FeaturesChronic bronchitis presents with a persistent productive cough and thick, sometimes purulent mucus due to airway inflammation, enlarged mucus glands, and goblet cell...
Chronic Obstructive Pulmonary Disease01:24

Chronic Obstructive Pulmonary Disease

COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
COPD: Management Using Bronchodilators and Corticosteroids01:26

COPD: Management Using Bronchodilators and Corticosteroids

Chronic obstructive pulmonary isease (COPD) involves a group of progressive lung disorders characterized by persistent airflow limitation and chronic respiratory symptoms. Asthma-COPD Overlap Syndrome (ACOS), encompassing features of both asthma and Chronic obstructive pulmonary disease (COPD), is a group of progressive lung disorders that includes chronic bronchitis, emphysema, and refractory (non-reversible) asthma. ACOS leads to complex clinical presentations that combine the inflammatory...
Chronic Obstructive Pulmonary Disease I: Introduction01:23

Chronic Obstructive Pulmonary Disease I: Introduction

Chronic obstructive pulmonary disease is a common, preventable, and treatable respiratory disorder characterized by persistent symptoms and progressive airflow limitation. This limitation results from a combination of small-airway disease (obstructive bronchiolitis) and parenchymal destruction (emphysema), both driven by chronic inflammation from exposure to harmful particles or gases.The disease includes two main pathological entities: emphysema, marked by destruction of alveolar walls and...

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Related Experiment Video

Updated: Jul 4, 2026

Alternative Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Moving Cupping Along Meridians
04:03

Alternative Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Moving Cupping Along Meridians

Published on: September 27, 2024

[Persistent cough and bronchiectasis].

W Bauer1, M Weise

  • 1Lungen- und Schlafzentrum Bern, Lindenhofspital, Bern.

Praxis
|July 3, 2008
PubMed
Summary
This summary is machine-generated.

Chronic cough in a 68-year-old woman resolved after diagnosing and treating obstructive sleep apnea (OSA). Micro-aspiration during apnea events is the presumed cause of persistent cough.

Related Experiment Videos

Last Updated: Jul 4, 2026

Alternative Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Moving Cupping Along Meridians
04:03

Alternative Therapy for Acute Exacerbation of Chronic Obstructive Pulmonary Disease: Moving Cupping Along Meridians

Published on: September 27, 2024

Area of Science:

  • Pulmonology
  • Sleep Medicine
  • Internal Medicine

Background:

  • A 68-year-old female presented with a chronic cough unresponsive to multiple treatments.
  • Previous diagnoses included bronchiectasis, asthma, carcinoid tumor, and coronary artery disease, all managed appropriately.
  • The persistent cough significantly impacted the patient's quality of life despite extensive medical interventions.

Observation:

  • The patient's chronic cough persisted despite physiotherapy, asthma control, surgical removal of a carcinoid tumor, and coronary artery revascularization.
  • Empirical treatments with antibiotics and systemic corticosteroids provided no relief.
  • A subsequent diagnosis of obstructive sleep apnea (OSA) was made.

Findings:

  • Treatment of obstructive sleep apnea (OSA) resulted in complete resolution of the chronic cough.
  • The patient became symptom-free after initiating OSA management.
  • This suggests a strong link between undiagnosed OSA and chronic cough.

Implications:

  • The findings suggest that micro-aspiration during apneic events may be a significant cause of chronic cough.
  • Obstructive sleep apnea (OSA) should be considered in the differential diagnosis of refractory chronic cough.
  • Timely diagnosis and treatment of OSA can lead to significant symptom improvement and enhanced patient well-being.