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Type A behaviour and risk of coronary heart disease: the JPHC Study
Ai Ikeda1, Hiroyasu Iso, Ichiro Kawachi
1Department of Social and Environmental Medicine, Graduate School of Medicine, Osaka University. Suita-shi, Osaka, Japan.
Insights
Type A behavior does not predict coronary heart disease (CHD) risk in Japanese adults. However, lower levels of Type A behavior were linked to increased CHD risk in Japanese men, suggesting gender-specific and cultural influences on cardiovascular health.
Area of Science:
- Cardiology
- Behavioral Science
- Epidemiology
Background:
- Type A behavior is linked to coronary heart disease (CHD) risk, but findings are mixed and understudied in Asian populations.
- Limited research exists on Type A behavior and CHD risk among Asian cohorts.
Purpose of the Study:
- To prospectively examine the association between Type A behavior and CHD incidence in a large Japanese cohort.
- To investigate potential gender-specific and culturally contingent effects of Type A behavior on cardiovascular risk.
Main Methods:
- A cohort of 86,361 Japanese men and women aged 40-69 years was followed from 1990-94 to January 2004.
- Incident coronary heart disease (CHD) cases (n=669) were identified and analyzed in relation to baseline Type A behavior scores.
Main Results:
- No overall association was found between Type A behavior and CHD incidence in the Japanese cohort.
- Japanese men with lower levels of Type A behavior exhibited a significantly increased risk of CHD (HR = 1.32).
- Women showed a non-significant trend towards reduced CHD risk with lower Type A behavior levels (HR = 0.79).
Conclusions:
- Type A behavior does not predict CHD incidence in the Japanese population.
- Lower Type A behavior (Type B patterns) may be associated with increased CHD risk in Japanese males.
- The cardiovascular impact of Type A behavior appears to be gender-specific and culturally dependent.
Background:
Although numerous studies of type A behaviour and risk of coronary heart disease (CHD) have been reported in the west (with mixed findings), few studies have been carried out in Asian populations.
Methods:
We examined prospectively the association between type A-behaviour and risk of CHD incidence within a cohort of 86 361 Japanese men and women aged 40-69 years. A total of 669 cases of newly diagnosed CHD occurred between the baseline questionnaire (1990-94) and the end of follow-up in January 2004.
Results:
We found no overall evidence of an association between type A and CHD incidence. The multivariate hazard ratio (HR) and 95% confidence intervals for CHD incidence in the highest vs lowest level of type A was 1.19 (0.94-1.51) overall. Contrary to expectation, Japanese men with lower levels of type A behaviour (lower levels of impatience, aggressiveness and competitiveness) appeared to be at significantly increased risk of CHD incidence (HR = 1.32; 95% CI 1.02-1.72). In contrast to men, there was insignificant but a tendency for reduced risk of CHD incidence (HR = 0.79, 95% CI 0.46-1.34) for women with lower levels of type A behaviour.
Conclusions:
Type A behaviour does not predict CHD incidence in the Japanese population. Among males, type B behavioural patterns appear to confer increased CHD risk. Our findings suggest that the cardio-toxic effect of type A behaviour is gender-specific and culturally contingent.
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