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Related Concept Videos

Production of Alcohol01:27

Production of Alcohol

Continuous fermentation is a key strategy in industrial ethanol production, particularly when efficiency, scalability, and high yields are essential. This approach allows for uninterrupted operation and optimized resource utilization. The primary feedstock, corn starch, undergoes enzymatic hydrolysis facilitated by α-amylase and glucoamylase. These enzymes break down the starch into fermentable sugars such as glucose, which are readily assimilated by fermentative microorganisms.Fermentation...
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Strain improvement is a foundational strategy in industrial microbiology aimed at maximizing microbial productivity, particularly because natural isolates typically yield commercially valuable products in very low concentrations. Although optimizing the culture medium and environmental conditions can improve yields, these adjustments are inherently limited by the organism’s genetic potential. As a result, the focus shifts toward genetic modifications to enhance biosynthetic capacity. The...
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Most eukaryotic organisms require oxygen to survive and function adequately. Such organisms produce large amounts of energy during aerobic respiration by metabolizing glucose and oxygen into carbon dioxide and water. However, most eukaryotes can generate some energy in the absence of oxygen by anaerobic metabolism.
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Continuous Liquid-Liquid Extraction of Medium-Chain Fatty Acids from Fermentation Broth Using Hollow-Fiber Membranes
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Ethanol extraction by supported liquid membrane during fermentation.

P Christen1, M Minier, H Renon

  • 1Centre Réacteurs et Processes, Ecole Nationale Supérieure des Mines de Paris, 60 boulevard Saint-Michel, 75006 Paris, France.

Biotechnology and Bioengineering
|June 20, 1990
PubMed
Summary
This summary is machine-generated.

A novel supported liquid membrane system enhances Saccharomyces bayanus fermentation by efficiently extracting ethanol. This boosts glucose conversion by 54% and 2.5x ethanol productivity, while purifying the product.

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Area of Science:

  • Biotechnology
  • Chemical Engineering
  • Fermentation Technology

Background:

  • Ethanol fermentation is crucial for biofuel and chemical production.
  • High ethanol concentrations inhibit yeast (Saccharomyces bayanus) performance.
  • Efficient ethanol removal is needed to improve fermentation efficiency.

Purpose of the Study:

  • To develop and evaluate a supported liquid membrane (SLM) system for in-situ ethanol extraction.
  • To assess the impact of SLM on Saccharomyces bayanus fermentation performance.
  • To investigate the purification capabilities of the SLM system.

Main Methods:

  • Fabrication of an SLM using a porous Teflon support soaked with isotridecanol.
  • Integration of the SLM into a semicontinuous fermentation of Saccharomyces bayanus.
  • Monitoring of fermentation parameters including glucose conversion, ethanol concentration, and yeast viability.

Main Results:

  • Ethanol extraction significantly reduced product inhibition, increasing glucose conversion from 293 g/L to 452 g/L.
  • Ethanol volumetric productivity was enhanced 2.5-fold due to improved yeast viability.
  • Substrate conversion yield remained above 95% of the theoretical value.
  • The SLM system demonstrated selectivity, separating ethanol from cells, substrate, and ions, achieving a four-fold concentration in the permeate.

Conclusions:

  • The developed SLM system is biocompatible, efficient, and stable for ethanol extraction.
  • In-situ ethanol removal via SLM effectively alleviates fermentation inhibition and enhances productivity.
  • This technology offers a promising approach for integrated ethanol production and purification.