Related Experiment Video
Updated: Jul 4, 2026

A TNBS-Induced Rodent Model to Study the Pathogenic Role of Mechanical Stress in Crohn's Disease
Published on: March 1, 2022
[Inflammatory cloacogenic polyp]
Roberto Calva-Rodríguez1, Mario Alberto González-Palafox, María Eugenia Rivera-Domínguez
1Facultad de Medicina, Benemérita Universidad Autónoma de Puebla.
Introduction:
Cloacogenic Polyps are characterized by the presence of inflammatory lesions in the lower rectum, and the anal transition zone. The polyps can prolaps; this is due to the malfunction of the internal anal sphincter; and the smooth muscle that covers the rectum. This is the result of the chronic inflammatory process. The lesions are more common in women during the third and fourth decade of life, however lesion have been described in 10 and 83 year olds. 85% lesions are located above the anal border and predominantly in the anterior lateral wall. The polyps vary in size from 3-4 cm in diameter, and have a sessile appearance.
Case Report:
10-year-old female presents with a 3-month history of irregular abdominal pain, with occasional vomiting, constipation, and occasional diarrhea.
Conclusions:
This entity of colon polyps is somewhat rare, and is seen in young adults; however its presence in infancy requires that we think of this entity when we formulate our differential diagnosis. Due to the character of the lesions, this entity could be confused with colorectal malignant tumors. All children and infants with a rectal mass, and blood in their stools should get a biopsy sent for histopathology. This technique can aid in analyzing the origin of the lesion.
Related Concept Videos
Inflammatory Bowel Disease II: Crohn's Disease
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by transmural...
Inflammatory Bowel Disease III: Crohn's Disease
Inflammatory Bowel Disease I: Introduction
Inflammatory Bowel Disease II: Ulcerative Colitis
Inflammatory Bowel Disease I: Ulcerative Colitis
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory Bowel Disease V: Surgical Management
Here are some common surgical interventions for IBD:
