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Published on: May 23, 2021
[Candida spondylodiscitis--review of the literature]
Małgorzata Łukjanowicz1, Andrzej Bohatyrewicz, Marek Brzosko
1Klinika Reumatologii Pomorskiej Akademii Medycznej w Szczecinie, Szczecin.
Abstract:
Infectious spondylodiscitis due to Candida species is rarely reported, not well known entity with low frequency. Most probably its frequency is underestimated, partly because of chronic course and difficulties with establishing of final diagnosis. Candida can be considered as the opportunistic pathogens. The infection proceeds as the systemic mycosis and most commonly develops in individuals with immune deficiency. In forthcoming years, the higher frequency of opportunistic infections, including mycotic spondylodiscitis, can be expected because of an increasing number of individuals treated with immunosuppressive drugs, and an increasing number of medical invasive procedures. A purpose of our paper is to describe a natural history of infectious spondylodiscitis due to Candida, usefull diagnostic methods, and recommended treatment.
Insights
Candida species rarely cause infectious spondylodiscitis, an underdiagnosed spinal infection. This review details its natural history, diagnosis, and treatment for this opportunistic fungal infection.
Area of Science:
- Mycology
- Infectious Diseases
- Spinal Infections
Context:
- Infectious spondylodiscitis caused by Candida species is a rare and underdiagnosed spinal infection.
- Candida species are opportunistic pathogens, typically causing systemic mycosis in immunocompromised individuals.
- Increasing use of immunosuppressive drugs and invasive procedures may lead to a higher incidence of mycotic spondylodiscitis.
Purpose:
- To describe the natural history of Candida-induced infectious spondylodiscitis.
- To outline effective diagnostic methods for this condition.
- To recommend appropriate treatment strategies for Candida spondylodiscitis.
Summary:
- Candida species are infrequent causes of infectious spondylodiscitis, often presenting with a chronic course and diagnostic challenges.
- This opportunistic fungal infection primarily affects immunocompromised patients.
- The paper aims to elucidate the natural progression, diagnostic approaches, and therapeutic interventions for Candida spondylodiscitis.
Impact:
- Enhances understanding of a rare but significant opportunistic spinal infection.
- Provides guidance for clinicians in diagnosing and managing Candida spondylodiscitis.
- Contributes to the literature on fungal infections in the context of increasing immunosuppression and medical interventions.
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