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Recurrence after ROLL lumpectomy for invasive breast cancer
H S J Ramesh1, S Anguille, L S Chagla
1Department of Surgery, Whiston Hospital, UK.
Breast (Edinburgh, Scotland)
|July 4, 2008
Summary
Radio-guided occult lesion localization (ROLL) effectively removes impalpable breast cancers. Long-term follow-up shows a low local recurrence rate of 1.98% after ROLL lumpectomy.
Area of Science:
- Oncology
- Surgical Oncology
- Radiology
Background:
- Radio-guided occult lesion localization (ROLL) is a technique for targeting impalpable breast lesions.
- While ROLL facilitates removal of sub-clinical breast lesions with minimal tissue excision, long-term outcome data were previously unavailable.
Purpose of the Study:
- To assess the rate of invasive breast cancer recurrence following lumpectomy performed using the ROLL technique.
Main Methods:
- A series of 151 patients with impalpable invasive breast cancers underwent ROLL excision between December 2002 and June 2006.
- Patients were monitored for local and systemic recurrence via clinical examinations and mammography.
- Suspicious lesions were pathologically confirmed, with additional imaging as clinically indicated.
Main Results:
- The median follow-up duration was 33 months, with a minimum of 22 months for all patients.
- A total of three local recurrences were observed among the 151 patients, resulting in a local recurrence rate of 1.98%.
Conclusions:
- The local recurrence rate for sub-clinical invasive breast cancer treated with radioisotope-guided excision (ROLL) is comparable to other localization methods.
- The study recommends the widespread implementation of ROLL for breast cancer treatment.
