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Synthesis and antihypertensive activity of some 2-aminobenzimidazole and indole derivatives
A Da Settimo1, A M Marini, G Primofiore
1Istituto di Chimica Farmaceutica dell'Università di Pisa, Italy.
Abstract:
The synthesis of some 2-aminobenzimidazole and indole amide derivatives containing a 2,6-dichloroaniline moiety is described. The preparation of a theophylline derivative is also reported. All the compounds tested showed no appreciable antihypertensive activity on spontaneously hypertensive rats.