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Updated: Jul 4, 2026

Isolation of Brain-infiltrating Leukocytes

Isolation of Brain-infiltrating Leukocytes

Published on: June 13, 2011

Multiloculated pyogenic brain abscess: experience in 25 patients.

Thung-Ming Su¹, Chu-Mei Lan, Yu-Duan Tsai

¹Department of Neurosurgery, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Kaohsiung, Taiwan.

|September 16, 2008

Summary

Multiloculated brain abscesses, comprising 20% of cases, show similar outcomes to uniloculated ones but require careful monitoring due to higher recurrence rates after surgery.

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Area of Science:

Neurosurgery
Infectious Diseases
Radiology

Background:

Pyogenic brain abscesses present diagnostic and therapeutic challenges.
Multiloculated abscesses represent a distinct subtype with potentially different clinical characteristics.

Purpose of the Study:

To compare bacteriology, predisposing factors, treatment, and outcomes of multiloculated versus uniloculated brain abscesses.
To evaluate the efficacy of surgical excision for multiloculated brain abscesses.

Main Methods:

Retrospective analysis of 124 patients with pyogenic brain abscess over 16 years.
Inclusion of 25 cases of multiloculated brain abscess for comparative analysis.

Main Results:

Multiloculated abscesses occurred in 20% of patients, with hematogenous spread as a common etiology.
Headache and hemiparesis were more frequent in multiloculated cases; fever in uniloculated.
Higher recurrence rates (38%) were observed in multiloculated abscesses post-surgery compared to uniloculated (13.1%).

Conclusions:

Surgical excision is recommended for multiloculated brain abscesses.
Prognosis is comparable between multiloculated and uniloculated abscesses, but vigilance for recurrence is crucial.
Careful post-operative monitoring is essential due to the significantly higher risk of recurrence in multiloculated brain abscesses.