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Colorimetric discrimination between important alkaloid nuclei mediated by a bis-salphen chromophore
Sander J Wezenberg1, Eduardo C Escudero-Adán, Jordi Benet-Buchholz
1Institute of Chemical Research of Catalonia (ICIQ), Av. Paisos Catalans 16, 43007 Tarragona, Spain.
Abstract:
A new colorimetric method is presented that allows for simple and effective discrimination between (iso)quinoline nuclei pertinent to many alkaloid species. The method is based on the reversible incorporation of Zn2+ ions into a bis-salphen chromophore under aqueous conditions. The metalation process is a function of the stability of the Zn-N (acceptor-donor) interaction and is accompanied by a clear colorimetric response.
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